Article: Papai E, Ntoh K, Zhang L, Yu JQ, Olszanski AJ, Villano AM, Porpiglia AS, Reddy SS, Farma JM, Greco SH. The Utility of Preoperative PET/CT in Patients with Clinically High-Risk Melanoma.  Ann Surg Oncol. 2025 Dec;32(13):9668-9675.   Understanding PET/CT Scans for Melanoma What is a PET/CT scan?  A PET/CT combines two imaging techniques: PET (positron emission tomography) shows cancer activity by detecting areas using high amounts of sugar, and CT (computed tomography)

Article: Effiom D, Cohen S. Nodal Management in Melanoma: Is Nodal Staging Needed, What Is the Value, and What Is the Extent of Surgery ? Surg Oncol Clin N Am. 2025 Jul;34(3):343-357   Understanding Lymph Node Management in Melanoma When melanoma spreads, it usually goes to nearby lymph nodes first. How doctors check and treat your lymph nodes has changed dramatically in recent years, especially with new immunotherapy drugs. Here's what you need to know.   What is a sentinel

Article: Hyngstrom JR. Neoadjuvant Therapy: Changes in the Management of Macroscopic Stage III/Resectable Stage IV Melanoma . Surg Oncol Clin N Am. 2025 Jul;34(3):375-392.    What is neoadjuvant therapy? "Neoadjuvant" means treatment given before surgery. Traditionally, melanoma that has spread to lymph nodes (stage III) or nearby areas was treated with surgery first, then medication afterward (adjuvant therapy). But recent research shows that giving immunotherapy before surg

Article: Tasdogan A, Sullivan RJ, Katalinic A, Lebbe C, Whitaker D, Puig S, van de Poll-Franse LV, Massi D, Schadendorf D. Cutaneous melanoma. Nat Rev Dis Primers. 2025 Apr 3;11(1):23.   Understanding Melanoma: A Patient's Guide What is melanoma?  Melanoma is skin cancer that develops from melanocytes—the cells that produce melanin, the pigment giving your skin its color. While most skin cancers stay in one place, melanoma is more serious because it can spread to other parts

Article: Farooq MS, Manahil Haider Jeoffrey S, Vargas GM, Karakousis GC. Margins for Melanoma: Extent of Resection, Alternative Approaches, and Future Considerations .   Surg Oncol Clin N Am. 2025 Jul;34(3):297-318   Understanding Surgical Margins for Melanoma When melanoma is diagnosed, your surgeon must remove the tumor along with some surrounding healthy skin—this border of healthy tissue is called the surgical margin. Getting the margin right is critical: too narrow and c